Echoes of Ancient Egyptian Innovations in Modern Science | May 10 2024, 23:23

A very interesting podcast about Ancient Egypt. https://www.youtube.com/watch?v=EDz45ELiquc

There, Viktor discusses how over thousands of years, at least two scientific disciplines—astronomy and medicine—were systematically developed in Egypt. In another segment, the host asks Viktor what he would do if he had a time machine. Viktor answered that he would like to hear how the speech of a king sounded (because we do not understand how the speech of the ancient Egyptians sounded, although we are familiar with their writing).

And here’s what I thought. Indeed, given a time machine, what could we bring back from the past that would be truly useful in the present? Obviously, 100% of Egyptian astronomy is useless to us from a scientific standpoint. But it’s a different story with medicine.

The fact is that the discovery of drugs is now largely done by trial and error (scientifically called “high-throughput screening” or HTS). HTS is a process of automated testing of a large number of chemical compounds for activity against a specific biological target (often a molecule, frequently a protein). The “hits” are then analyzed, followed by many more tests on organisms, where 99% are filtered out for various reasons. And there is hope that eventually, this will lead to a working drug.

Thus, in ancient medicine, things were simpler ethics-wise, and they immediately tested on humans. Take a poisonous mushroom and feed it to the sick in the hope of curing them. If the patient died, but (hypothetically) his hair grew, then it would make sense to give half the dose to someone who needed hair. Oh, he died too. So, next time we give a quarter.

So, it is generally useful for modern medicine to look back at ancient books.

One notable example is the development of artemisinin, a drug against malaria, inspired by an ancient Chinese text. Under the leadership of Tu Youyou, the team analyzed about 2000 ancient recipes and based on 640 selected prescriptions, they produced 380 extracts, which were tested on animals. In 1971, one of these, artemisinin, showed good antimalarial properties. It was manufactured from the plant Artemisia annua, following a recipe from the third part of Ge Hong’s book “Zhouhou Beiji Fang” (“Emergency Prescriptions at an Elbow’s Reach”), dating back to AD 340. Tu Youyou and her team isolated artemisinin from the plant, which proved to be very effective against malaria. This discovery earned Tu Youyou the Nobel Prize in Physiology or Medicine in 2015.

About Egypt, look it up. Viktor Solkin is very knowledgeable.

https://www.youtube.com/watch?v=EDz45ELiquc

Exploring the Urban Elegance of Joseph Zbukvic’s Watercolors | May 10 2024, 12:45

Perhaps, Croatian artist Joseph Zbukvic is the best watercolorist among contemporaries. The only disappointment is that he only paints urban landscapes, sometimes featuring horses. The world deserves more 🙂 Take a look at his works! I always watch watercolorists with great interest and admiration because their technique does not forgive mistakes.

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Exploring Sheet Sage: Converting MP3 to Sheet Music | May 09 2024, 21:47

I played around a bit with converting mp3 music into sheet music. It’s called Sheet Sage. You feed it a YouTube link, and it spits out a PDF with sheet music and a midi file. The result isn’t exactly great, but it’s better than I expected. Here are two videos—one with the original track, the other with how the midi sounds (I changed the default instruments a bit), and the sheet music right here.

original:

how it sounds:

Exploring the Photorealistic Art of Vladimir Davydenko | May 08 2024, 18:20

I continue my series on fascinating artists. Artist Vladimir Davydenko (born in 1966) currently resides and creates his art in Moscow. His expertise spans several genres: portraits and still lifes, landscapes, and paintings with religious themes, yet all exhibit a photorealistic style. All posts similar to this can be found at https://beinginamerica.com/category/art-rauf-likes/.

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Liza’s Budget-Friendly European Adventures | May 07 2024, 12:29

Liza is currently in Germany. Or rather, well… she spends more time in Germany than anywhere else. She’s taking full advantage of the opportunity to study in Europe. From her base in Braunschweig, over the past month, she has visited Prague, Berlin, Hanover, Hamburg, London, and most recently Munich last weekend. Liza is on a tight budget, and her trips are all about maximizing savings. She bought a monthly pass (apparently a BahnCard) that covers, conditionally, all regional trains in Germany. But because of this, her routes to destinations tend to be rather circuitous. For example, it took her 10 hours to get to Munich from Braunschweig using regional trains, and 13 hours to get back. The trip to Munich included 9 changes, including at Herzberg, Nordhausen, Leinefelde, Bad Langensalza, Augsburg, Nürnberg, Seesen, Erfurt. On her way back, she accidentally boarded the wrong train, which added a few more changes and an extra three hours to her journey. Isn’t she a hero?

She is now planning a ten-day trip to the Netherlands, Belgium, and France next week. Wow, I’m jealous.

Exploring Femininity: The Oil Paintings of Mary Qian | May 07 2024, 02:51

American artist of Chinese descent, Mary Qian (born 1973 in Shanghai) currently lives and works in Chicago, engaging in graphic design, but also dedicates several hours each day to painting. Primarily using oil paints, the main subject of her work is the female figure. Stunning works!

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